DOSE:	112.5 mg	oral	Pharms - Venlafaxine	(daily)
		oral	LSD

BODY WEIGHT:

135 lb

I've been taking Effexor extended release (Venlafaxine) for almost a year now for treatment of depression, currently 112.5mg/day. Prior to being on effexor, I had tripped many times with LSD and with mushrooms (psilocybes). Since starting on effexor, I have found that the effects of shrooms, and especially acid, are greatly diminished in comparison to similar doses when not on effexor. Friends who I regularly tripped with were having a great time, saying this was the best acid that had come around in a while, and I was barely feeling anything. The best way I can describe it is this: the trips started, but never got off the ground. About an hour or so after eating a few hits, i started to get the typical body energy thing that usually escalated into full-on trip, but the trip never came. I basically had a mild body trip for a few hours but there were no visuals (other than maybe some mild peripheral tracers) and worst of all, there was no head trip whatsoever. So I felt like i was tripping physically for a few hours and couldn't sleep, but my state of mind was absolutely sober.

This has been my experience each time I have tried acid or mushrooms since being on effexor. Not necessarily a reason to go off of an anti-depressant, but certainly a very unfortunate side-effect. I've seen some other similar accounts with effexor and other ssri's and psychedelics, but I just thought I'd add mine.
-Be safe, Be wise. Know yourself, Know your drugs.

Exp Year: 2004	ExpID: 35488
Gender: Male
Age at time of experience: Not Given
Published: Oct 6, 2004	Views: 24,868
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Pharms - Venlafaxine (191), LSD (2) : Combinations (3), Unknown Context (20)